Gene
cd247
- ID
- ZDB-GENE-061130-4
- Name
- CD247 molecule
- Symbol
- cd247 Nomenclature History
- Previous Names
-
- cd3zeta
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in intestine; lymphocyte; ovary; and spleen. Orthologous to human CD247 (CD247 molecule).
- Genome Resources
-
- Alliance (1)
- Gene:100101654 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 25 | Alliance | ?Immunodeficiency 25 | 610163 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Phosphorylated immunoreceptor signalling ITAM | T-cell surface glycoprotein CD3 zeta subunit | T-cell surface glycoprotein CD3 zeta subunit/High affinity IgE receptor gamma subunit |
|---|---|---|---|---|
|
UniProtKB:A7KX13
|
153 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance