Gene
cyp4v2a
- ID
- ZDB-GENE-061103-601
- Name
- cytochrome P450, family 4, subfamily V, member 2a
- Symbol
- cyp4v2a Nomenclature History
- Previous Names
-
- cyp4v2
- cyp4v8 (3)
- im:7136890
- wu:fd50b03
- zgc:154161
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be located in membrane. Is expressed in eye; intestinal bulb; liver; and retina. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Orthologous to human CYP4V2 (cytochrome P450 family 4 subfamily V member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7136890 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bietti crystalline corneoretinal dystrophy | Alliance | Bietti crystalline corneoretinal dystrophy | 210370 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 Monooxygenases | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0JMQ6
|
513 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp4v8-201
(1)
|
Ensembl | 2,486 nt | ||
| ncRNA |
cyp4v8-002
(1)
|
Ensembl | 735 nt |
Interactions and Pathways
No data available
Plasmids
No data available