Gene
agpat2
- ID
- ZDB-GENE-061103-541
- Name
- 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
- Symbol
- agpat2 Nomenclature History
- Previous Names
-
- zgc:153984
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidic acid biosynthetic process. Predicted to localize to endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 1 and lipodystrophy. Orthologous to several human genes including AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Zhao et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital generalized lipodystrophy type 1 | Alliance | Lipodystrophy, congenital generalized, type 1 | 608594 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 1-acyl-sn-glycerol-3-phosphate acyltransferase | Phospholipid/glycerol acyltransferase |
|---|---|---|---|
|
UniProtKB:A0JMM2
|
271 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available