Gene
capn5a
- ID
- ZDB-GENE-061103-214
- Name
- calpain 5a
- Symbol
- capn5a Nomenclature History
- Previous Names
-
- zgc:153446
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in neovascular inflammatory vitreoretinopathy. Is expressed in hatching gland; nervous system; and optic vesicle. Orthologous to human CAPN5 (calpain 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neovascular inflammatory vitreoretinopathy | Alliance | Vitreoretinopathy, neovascular inflammatory | 193235 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR000169 | Cysteine peptidase, cysteine active site |
| Domain | IPR000008 | C2 domain |
| Domain | IPR001300 | Peptidase C2, calpain, catalytic domain |
| Domain | IPR022682 | Peptidase C2, calpain, large subunit, domain III |
| Domain | IPR022683 | Peptidase C2, calpain, domain III |
| Domain | IPR033883 | Calpain subdomain III |
| Domain | IPR033884 | Calpain C2 domain |
| Family | IPR022684 | Peptidase C2, calpain family |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036213 | Calpain large subunit, domain III superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | Calpain C2 domain | Calpain large subunit, domain III superfamily | Calpain subdomain III | Cysteine peptidase, cysteine active site | Papain-like cysteine peptidase superfamily | Peptidase C2, calpain, catalytic domain | Peptidase C2, calpain, domain III | Peptidase C2, calpain family | Peptidase C2, calpain, large subunit, domain III |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0JMG3
|
639 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
capn5a-201
(1)
|
Ensembl | 3,698 nt | ||
| mRNA |
capn5a-202
(1)
|
Ensembl | 2,051 nt | ||
| mRNA |
capn5a-203
(1)
|
Ensembl | 1,921 nt |
Interactions and Pathways
No data available
Plasmids
No data available