Gene
zgc:152891
- ID
- ZDB-GENE-061013-229
- Name
- zgc:152891
- Symbol
- zgc:152891 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. Predicted to be involved in linoleic acid metabolic process and lipid oxidation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1; autosomal recessive congenital ichthyosis 2; and autosomal recessive congenital ichthyosis 3. Orthologous to human ALOX12B (arachidonate 12-lipoxygenase, 12R type); ALOX15B (arachidonate 15-lipoxygenase type B); and ALOXE3 (arachidonate lipoxygenase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020834 | Lipoxygenase, conserved site |
| Domain | IPR001024 | PLAT/LH2 domain |
| Domain | IPR013819 | Lipoxygenase, C-terminal |
| Family | IPR000907 | Lipoxygenase |
| Family | IPR001885 | Lipoxygenase, mammalian |
| Homologous_superfamily | IPR036226 | Lipoxigenase, C-terminal domain superfamily |
| Homologous_superfamily | IPR036392 | PLAT/LH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | Lipoxigenase, C-terminal domain superfamily | Lipoxygenase | Lipoxygenase, conserved site | Lipoxygenase, C-terminal | Lipoxygenase, mammalian | PLAT/LH2 domain | PLAT/LH2 domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QKM3
|
663 | |||||||
|
UniProtKB:B2GSC9
|
611 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:152891-201
(1)
|
Ensembl | 2,204 nt | ||
| mRNA |
zgc:152891-202
(1)
|
Ensembl | 4,997 nt | ||
| mRNA |
zgc:152891-203
(1)
|
Ensembl | 1,862 nt |
Interactions and Pathways
No data available
Plasmids
No data available