Gene
plxna1b
- ID
- ZDB-GENE-061007-1
- Name
- plexin A1b
- Symbol
- plxna1b Nomenclature History
- Previous Names
-
- plxna1
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have semaphorin receptor activity. Involved in sprouting angiogenesis and wound healing. Predicted to localize to integral component of membrane. Is expressed in several structures, including nervous system; optic vesicle; otic vesicle; presumptive neural retina; and spinal cord neural tube. Orthologous to human PLXNA1 (plexin A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Dworschak-Punetha neurodevelopmental syndrome | 619955 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001627 | Sema domain |
| Domain | IPR002909 | IPT domain |
| Domain | IPR013548 | Plexin, cytoplasmic RasGAP domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR041019 | Plexin, TIG domain 1 |
| Domain | IPR041362 | Plexin, TIG domain 2 |
| Domain | IPR042744 | Plexin-A1, Sema domain |
| Domain | IPR046800 | Plexin, cytoplasmic RhoGTPase-binding domain |
| Family | IPR031148 | Plexin family |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036352 | Sema domain superfamily |
| Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
| Protein | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Plexin-A1, Sema domain | Plexin, cytoplasmic RasGAP domain | Plexin, cytoplasmic RhoGTPase-binding domain | Plexin family | Plexin repeat | Plexin, TIG domain 1 | Plexin, TIG domain 2 | PSI domain | Rho GTPase activation protein | Sema domain | Sema domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A8IYK2
|
1885 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plxna1-201
(1)
|
Ensembl | 5,658 nt |
Interactions and Pathways
No data available
Plasmids
No data available