Gene
ugt2a5
- ID
- ZDB-GENE-060929-796
- Name
- UDP glucuronosyltransferase 2 family, polypeptide A5
- Symbol
- ugt2a5 Nomenclature History
- Previous Names
-
- zgc:153113
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable glucuronosyltransferase activity. Predicted to be located in membrane. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B11 (UDP glucuronosyltransferase family 2 member B11); and UGT2B15 (UDP glucuronosyltransferase family 2 member B15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | UDP-glucuronosyl/UDP-glucosyltransferase | UDP-glycosyltransferase | UDP-glycosyltransferase family, conserved site |
|---|---|---|---|---|
|
UniProtKB:F1RDD2
|
532 | |||
|
UniProtKB:B8JMA2
|
532 | |||
|
UniProtKB:A0A8M3B035
|
290 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ugt2a5-201
(1)
|
Ensembl | 2,542 nt | ||
| mRNA |
ugt2a5-202
(1)
|
Ensembl | 2,469 nt | ||
| mRNA |
ugt2a5-203
(1)
|
Ensembl | 951 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-204E18 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:153113 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:171316 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001076643 (1) | 2003 nt | ||
| Genomic | GenBank:BX072578 (1) | 183498 nt | ||
| Polypeptide | UniProtKB:B8JMA2 (1) | 532 aa |
No data available
- Wang, Y., Huang, H., Wu, Q. (2014) Characterization of the Zebrafish Ugt Repertoire Reveals a New Class of Drug-metabolizing UDP Glucuronosyltransferases. Molecular pharmacology. 86(1):62-75
- Huang, H., and Wu, Q. (2010) Cloning and comparative analyses of the zebrafish ugt repertoire reveal its evolutionary diversity. PLoS One. 5(2):e9144
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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