Gene

mgp

ID

ZDB-GENE-060928-1

Name

matrix Gla protein

Symbol

mgp Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Predicted to localize to collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in arteriosclerosis; calcinosis; and myocardial infarction. Is expressed in caudal fin; gill filament; sensory system; skeletal system; and trabecular layer. Orthologous to human MGP (matrix Gla protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mgp Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Keutel syndrome	245150

Associated With mgp Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000294	Gamma-carboxyglutamic acid-rich (GLA) domain
Family	IPR027118	Matrix Gla protein
Homologous_superfamily	IPR035972	Gamma-carboxyglutamic acid-rich (GLA) domain superfamily