Gene
spi1a
- ID
- ZDB-GENE-060825-351
- Name
- Spi-1 proto-oncogene a
- Symbol
- spi1a Nomenclature History
- Previous Names
-
- spi1l (1)
- zgc:152991
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in regulation of myeloid leukocyte differentiation. Predicted to localize to nucleus. Is expressed in anterior lateral plate mesoderm; intermediate cell mass of mesoderm; kidney; rostral blood island; and yolk. Orthologous to human SPI1 (Spi-1 proto-oncogene) and SPIB (Spi-B transcription factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
agammaglobulinemia 10 | Alliance | Agammaglobulinemia 10, autosomal dominant | 619707 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Ets domain | ETS family | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
---|---|---|---|---|---|
UniProtKB:A0A8M6Z4D3
|
248 | ||||
UniProtKB:F1QFB6
|
257 | ||||
UniProtKB:Q0P4E9
|
247 |
Interactions and Pathways
No data available
Plasmids
No data available