Gene
stra6
- ID
- ZDB-GENE-060616-252
- Name
- signaling receptor and transporter of retinol STRA6
- Symbol
- stra6 Nomenclature History
- Previous Names
-
- im:7151282
- wu:fc51h06
- zgc:136689 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Exhibits calmodulin binding activity and identical protein binding activity. Involved in chordate embryonic development and retinol transport. Localizes to integral component of plasma membrane. Used to study Matthew-Wood syndrome. Human ortholog(s) of this gene implicated in Matthew-Wood syndrome. Is expressed in several structures, including hindbrain neural plate; immature eye; nervous system; pleuroperitoneal region; and trunk. Orthologous to human STRA6 (signaling receptor and transporter of retinol STRA6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151282 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Isken et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| syndromic microphthalmia 9 | Alliance | Microphthalmia, isolated, with coloboma 8 | 601186 |
| syndromic microphthalmia 9 | Alliance | Microphthalmia, syndromic 9 | 601186 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR026612 | Receptor for retinol uptake STRA6-like |
Domain Details Per Protein
| Protein | Length | Receptor for retinol uptake STRA6-like |
|---|---|---|
|
UniProtKB:A0A8M9PGX1
|
670 | |
|
UniProtKB:F1RAX4
|
670 |
Interactions and Pathways
No data available
Plasmids
No data available