Gene
rxfp2l
- ID
- ZDB-GENE-060531-8
- Name
- relaxin family peptide receptor 2, like
- Symbol
- rxfp2l Nomenclature History
- Previous Names
-
- leugpcr (1)
- si:ch211-124k10.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled peptide receptor activity. Predicted to be involved in activation of adenylate cyclase activity; adenylate cyclase-activating G protein-coupled receptor signaling pathway; and hormone-mediated signaling pathway. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in cryptorchidism. Is expressed in several structures, including brain; liver; oral epithelium; retinal neural layer; and trigeminal ganglion. Orthologous to human RXFP2 (relaxin family peptide receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d0367 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023415 | Low-density lipoprotein (LDL) receptor class A, conserved site |
| Domain | IPR017452 | GPCR, rhodopsin-like, 7TM |
| Family | IPR000276 | G protein-coupled receptor, rhodopsin-like |
| Family | IPR008112 | Relaxin receptor |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Homologous_superfamily | IPR036055 | LDL receptor-like superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR002172 | Low-density lipoprotein (LDL) receptor class A repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | LDL receptor-like superfamily | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | Low-density lipoprotein (LDL) receptor class A, conserved site | Low-density lipoprotein (LDL) receptor class A repeat | Relaxin receptor |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3ASL6
|
668 | |||||||||
|
UniProtKB:A0A8M9PR12
|
644 | |||||||||
|
UniProtKB:A0A8M9PK07
|
668 | |||||||||
|
UniProtKB:B0S5B5
|
692 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rxfp2l-201
(1)
|
Ensembl | 2,132 nt | ||
| mRNA |
rxfp2l-202
(1)
|
Ensembl | 1,102 nt |
Interactions and Pathways
No data available
Plasmids
No data available