Gene

f11r.2

ID

ZDB-GENE-060531-67

Name

F11 receptor, tandem duplicate 2

Symbol

f11r.2 Nomenclature History

Previous Names

f11rl
jam1b (1)
jama2 (1)
si:ch211-89p1.1

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to be involved in establishment of endothelial intestinal barrier; intestinal absorption; and regulation of membrane permeability. Predicted to act upstream of or within cell adhesion. Predicted to be located in cell junction and plasma membrane. Predicted to be active in bicellular tight junction. Is expressed in several structures, including immature eye; integument; otic vesicle; pronephric duct; and sensory system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Powell et al., 2012

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With f11r.2 Human Ortholog

No data available

Associated With f11r.2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR042456	Junctional adhesion molecule A
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily