Gene
f11r.2
- ID
- ZDB-GENE-060531-67
- Name
- F11 receptor, tandem duplicate 2
- Symbol
- f11r.2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to be involved in establishment of endothelial intestinal barrier; intestinal absorption; and regulation of membrane permeability. Predicted to act upstream of or within cell adhesion. Predicted to be located in cell junction and plasma membrane. Predicted to be active in bicellular tight junction. Is expressed in several structures, including immature eye; integument; otic vesicle; pronephric duct; and sensory system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Powell et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Immunoglobulin V-set domain | Junctional adhesion molecule A |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B9L1
|
227 | |||||||
|
UniProtKB:A3KNL2
|
294 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
f11r.2-201
(1)
|
Ensembl | 1,428 nt | ||
| mRNA |
f11r.2-202
(1)
|
Ensembl | 847 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-99I6 | ZFIN Curated Data | |
| Contained in | BAC | CH211-89P1 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:162181 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001082982 (1) | 1453 nt | ||
| Genomic | GenBank:BX510918 (1) | 199447 nt | ||
| Polypeptide | UniProtKB:A3KNL2 (1) | 294 aa |
- Xie, C., Zheng, N., Li, M., Zhang, Z., Huang, D., Xiao, M., Chen, D., He, C., Zuo, Z., Chen, X. (2024) Comparative Analysis of Therapeutic Efficacy and Adverse Reactions among Various Thrombolytic Agents. Toxics. 12(7):
- Kobayashi, I., Kobayashi-Sun, J., Kim, A.D., Pouget, C., Fujita, N., Suda, T., Traver, D. (2014) Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling. Nature. 512(7514):319-23
- Powell, G.T., and Wright, G.J. (2012) Genomic organisation, embryonic expression and biochemical interactions of the zebrafish junctional adhesion molecule family of receptors. PLoS One. 7(7):e40810
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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