Gene
cacna1ba
- ID
- ZDB-GENE-060531-44
- Name
- calcium channel, voltage-dependent, N type, alpha 1B subunit, a
- Symbol
- cacna1ba Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have voltage-gated calcium channel activity. Predicted to be involved in calcium ion import and chemical synaptic transmission. Predicted to localize to voltage-gated calcium channel complex. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome and dystonia 23. Is expressed in atrium; brain; cardiac ventricle; and liver. Orthologous to human CACNA1B (calcium voltage-gated channel subunit alpha1 B).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements | 618497 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR005821 | Ion transport domain |
Domain | IPR014873 | Voltage-dependent calcium channel, alpha-1 subunit, IQ domain |
Domain | IPR031649 | Voltage-dependent L-type calcium channel, IQ-associated domain |
Family | IPR002077 | Voltage-dependent calcium channel, alpha-1 subunit |
Family | IPR005447 | Voltage-dependent calcium channel, N-type, alpha-1 subunit |
Family | IPR050599 | Voltage-dependent calcium channel alpha-1 subunit |
Homologous_superfamily | IPR027359 | Voltage-dependent channel domain superfamily |
Domain Details Per Protein
Protein | Length | Ion transport domain | Voltage-dependent calcium channel alpha-1 subunit | Voltage-dependent calcium channel, alpha-1 subunit | Voltage-dependent calcium channel, alpha-1 subunit, IQ domain | Voltage-dependent calcium channel, N-type, alpha-1 subunit | Voltage-dependent channel domain superfamily | Voltage-dependent L-type calcium channel, IQ-associated domain |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3AZM5
|
2357 | |||||||
UniProtKB:A0A8M9Q3D8
|
2365 | |||||||
UniProtKB:A0A8M6Z0K7
|
2369 | |||||||
UniProtKB:A0A8M3ASG9
|
2378 | |||||||
UniProtKB:T2B1R0
|
2194 | |||||||
UniProtKB:A0A8M9Q3C7
|
2376 | |||||||
UniProtKB:A0A8M3B9N2
|
2351 | |||||||
UniProtKB:A0A8M9QE01
|
2205 | |||||||
UniProtKB:A0A8M3B2I1
|
2367 | |||||||
UniProtKB:A0A8M9PK68
|
2344 | |||||||
UniProtKB:A0A8M9QDZ5
|
2374 | |||||||
UniProtKB:A0A8M9Q8P2
|
2346 | |||||||
UniProtKB:A0A8M6Z6W1
|
2364 | |||||||
UniProtKB:A0A8M9PXN1
|
2365 | |||||||
UniProtKB:A0A8M6YY83
|
2355 | |||||||
UniProtKB:A0A8M9Q8N7
|
2371 | |||||||
UniProtKB:A0A8M9PXL9
|
2378 | |||||||
UniProtKB:A2BHF4
|
2312 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
cacna1ba-201
(1)
|
Ensembl | 6,939 nt | ||
mRNA |
cacna1ba-202
(1)
|
Ensembl | 6,813 nt | ||
mRNA |
cacna1ba-203
(1)
|
Ensembl | 6,585 nt |
Interactions and Pathways
No data available
Plasmids
No data available