Gene

slc8a2a

ID

ZDB-GENE-060531-155

Name

solute carrier family 8 member 2a

Symbol

slc8a2a Nomenclature History

Previous Names

ncx2a (1)
si:dkey-85k8.4

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have calcium:sodium antiporter activity. Predicted to be involved in calcium ion transport; cell communication; and transmembrane transport. Predicted to localize to integral component of membrane. Is expressed in ovary. Orthologous to human SLC8A2 (solute carrier family 8 member A2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Liao et al., 2007

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc8a2a Human Ortholog

No data available

Associated With slc8a2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003644	Na-Ca exchanger/integrin-beta4
Domain	IPR004837	Sodium/calcium exchanger membrane region
Domain	IPR032452	Sodium/calcium exchanger domain, C-terminal extension
Family	IPR004836	Sodium/calcium exchanger protein
Family	IPR051171	Calcium/Cation Antiporter
Homologous_superfamily	IPR038081	CalX-like domain superfamily
Homologous_superfamily	IPR044880	NCX, central ion-binding domain superfamily

Domain Details Per Protein

Protein	Length	Calcium/Cation Antiporter	CalX-like domain superfamily	Na-Ca exchanger/integrin-beta4	NCX, central ion-binding domain superfamily	Sodium/calcium exchanger domain, C-terminal extension	Sodium/calcium exchanger membrane region	Sodium/calcium exchanger protein
UniProtKB:A0A8M3ASJ4 InterPro	919
UniProtKB:A0A8M3ASJ9 InterPro	682
UniProtKB:A0A286Y8H6 InterPro	891
UniProtKB:A0A8M3B9T8 InterPro	913
UniProtKB:A0A8M3AZU6 InterPro	857
UniProtKB:B2CZC3 InterPro	891
UniProtKB:A0A8M3ASN9 InterPro	897
UniProtKB:A0A8M3B9U2 InterPro	676