Gene

atp2a3

ID

ZDB-GENE-060531-103

Name

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3

Symbol

atp2a3 Nomenclature History

Previous Names

si:dkey-205l20.1

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have calcium transmembrane transporter activity, phosphorylative mechanism and proton-exporting ATPase activity, phosphorylative mechanism. Predicted to be involved in calcium ion transmembrane transport and cellular calcium ion homeostasis. Predicted to localize to sarcoplasmic reticulum membrane. Is expressed in Purkinje cell. Orthologous to human ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atp2a3 Human Ortholog

No data available

Associated With atp2a3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004014	Cation-transporting P-type ATPase, N-terminal
Domain	IPR006068	Cation-transporting P-type ATPase, C-terminal
Domain	IPR044492	P-type ATPase, haloacid dehalogenase domain
Family	IPR001757	P-type ATPase
Family	IPR005782	P-type ATPase, subfamily IIA, SERCA-type
Homologous_superfamily	IPR008250	P-type ATPase, A domain superfamily
Homologous_superfamily	IPR023214	HAD superfamily
Homologous_superfamily	IPR023298	P-type ATPase, transmembrane domain superfamily
Homologous_superfamily	IPR023299	P-type ATPase, cytoplasmic domain N
Homologous_superfamily	IPR036412	HAD-like superfamily
PTM	IPR018303	P-type ATPase, phosphorylation site

Domain Details Per Protein

Protein	Length	Cation-transporting P-type ATPase, C-terminal	Cation-transporting P-type ATPase, N-terminal	HAD-like superfamily	HAD superfamily	P-type ATPase	P-type ATPase, A domain superfamily	P-type ATPase, cytoplasmic domain N	P-type ATPase, haloacid dehalogenase domain	P-type ATPase, phosphorylation site	P-type ATPase, subfamily IIA, SERCA-type	P-type ATPase, transmembrane domain superfamily
UniProtKB:A0A2R8QJH4 InterPro	1005
UniProtKB:F1Q4P9 InterPro	991

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	atp2a3-201 (1) Ensembl	Ensembl	5,899 nt	Select Tool ZFIN BLAST
mRNA	atp2a3-202 (1) Ensembl	Ensembl	5,467 nt	Select Tool
mRNA	atp2a3-203 (1) Ensembl	Ensembl	5,870 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations