Gene

eral1

ID

ZDB-GENE-060526-84

Name

Era-like 12S mitochondrial rRNA chaperone 1

Symbol

eral1 Nomenclature History

Previous Names

si:ch211-207c6.1

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have rRNA binding activity and ribosomal small subunit binding activity. Predicted to be involved in ribosomal small subunit assembly. Predicted to localize to mitochondrial matrix. Human ortholog(s) of this gene implicated in Perrault syndrome 6. Orthologous to human ERAL1 (Era like 12S mitochondrial rRNA chaperone 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eral1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Perrault syndrome 6	Alliance	Perrault syndrome 6	617565

Associated With eral1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004044	K Homology domain, type 2
Domain	IPR005225	Small GTP-binding domain
Domain	IPR006073	GTP binding domain
Domain	IPR030388	Era-type guanine nucleotide-binding (G) domain
Family	IPR005662	GTPase Era-like
Homologous_superfamily	IPR009019	K homology domain superfamily, prokaryotic type
Homologous_superfamily	IPR015946	K homology domain-like, alpha/beta
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	Era-type guanine nucleotide-binding (G) domain	GTPase Era-like	GTP binding domain	K homology domain-like, alpha/beta	K homology domain superfamily, prokaryotic type	K Homology domain, type 2	P-loop containing nucleoside triphosphate hydrolase	Small GTP-binding domain
UniProtKB:B0S6U7 InterPro	447

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	eral1-201 (1) Ensembl	Ensembl	1,754 nt	Select Tool
ncRNA	eral1-002 (1) Ensembl	Ensembl	810 nt	Select Tool
ncRNA	eral1-003 (1) Ensembl	Ensembl	1,754 nt	Select Tool
ncRNA	eral1-004 (1) Ensembl	Ensembl	527 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations