Gene

kiss1rb

ID

ZDB-GENE-060526-54

Name

KISS1 receptor b

Symbol

kiss1rb Nomenclature History

Previous Names

kiss2r (1)
KissR3 (1)
si:ch211-157p22.8

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Exhibits neuropeptide receptor activity. Involved in positive regulation of transcription, DNA-templated. Localizes to cell surface; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in gonadal disease; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Is expressed in several structures, including brain; fat cell; head; liver; and pleuroperitoneal region. Orthologous to human KISS1R (KISS1 receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kiss1rb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
central precocious puberty 1	Alliance	?Precocious puberty, central, 1	176400
hypogonadotropic hypogonadism 8 with or without anosmia	Alliance	Hypogonadotropic hypogonadism 8 with or without anosmia	614837

Associated With kiss1rb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR008103	KiSS-1 peptide receptor

Domain Details Per Protein

Protein	Length	GPCR, rhodopsin-like, 7TM	G protein-coupled receptor, rhodopsin-like	KiSS-1 peptide receptor
UniProtKB:A8CAH4 InterPro	364
UniProtKB:F1QZU4 InterPro	364
UniProtKB:A0A8M3B305 InterPro	276

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	kiss1rb-201 (1) Ensembl	Ensembl	1,095 nt	Select Tool
mRNA	kiss1rb-202 (1) Ensembl	Ensembl	720 nt	Select Tool ZFIN BLAST
mRNA	kiss1rb-203 (1) Ensembl	Ensembl	970 nt	Select Tool ZFIN BLAST
mRNA	kiss1rb-204 (1) Ensembl	Ensembl	1,179 nt	Select Tool ZFIN BLAST
mRNA	kiss1rb-205 (1) Ensembl	Ensembl	1,029 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations