Gene
man2a1
- ID
- ZDB-GENE-060526-31
- Name
- mannosidase, alpha, class 2A, member 1
- Symbol
- man2a1 Nomenclature History
- Previous Names
-
- si:ch211-131c14.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing and protein deglycosylation. Predicted to act upstream of or within mannose metabolic process. Predicted to be located in membrane. Predicted to be active in Golgi membrane. Orthologous to human MAN2A1 (mannosidase alpha class 2A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bergen et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000602 | Glycoside hydrolase family 38, N-terminal domain |
| Domain | IPR011682 | Glycosyl hydrolase family 38, C-terminal |
| Domain | IPR015341 | Glycoside hydrolase family 38, central domain |
| Family | IPR050843 | Glycosyl Hydrolase Family 38 |
| Homologous_superfamily | IPR011013 | Galactose mutarotase-like domain superfamily |
| Homologous_superfamily | IPR011330 | Glycoside hydrolase/deacetylase, beta/alpha-barrel |
| Homologous_superfamily | IPR013780 | Glycosyl hydrolase, all-beta |
| Homologous_superfamily | IPR027291 | Glycoside hydrolase 38, N-terminal domain superfamily |
| Homologous_superfamily | IPR028995 | Glycoside hydrolase families 57/38, central domain superfamily |
| Homologous_superfamily | IPR037094 | Glycoside hydrolase family 38, central domain superfamily |
Domain Details Per Protein
| Protein | Length | Galactose mutarotase-like domain superfamily | Glycoside hydrolase 38, N-terminal domain superfamily | Glycoside hydrolase/deacetylase, beta/alpha-barrel | Glycoside hydrolase families 57/38, central domain superfamily | Glycoside hydrolase family 38, central domain | Glycoside hydrolase family 38, central domain superfamily | Glycoside hydrolase family 38, N-terminal domain | Glycosyl hydrolase, all-beta | Glycosyl Hydrolase Family 38 | Glycosyl hydrolase family 38, C-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IVS5
|
1150 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
man2a1-201
(1)
|
Ensembl | 4,037 nt | ||
| mRNA |
man2a1-202
(1)
|
Ensembl | 1,434 nt |
Interactions and Pathways
No data available
Plasmids
No data available