Gene

adamts8a

ID
ZDB-GENE-060526-202
Name
ADAM metallopeptidase with thrombospondin type 1 motif, 8a
Symbol
adamts8a Nomenclature History
Previous Names
  • ADAMTS8d (1)
  • si:dkey-127j5.2
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase activity and zinc ion binding activity. Predicted to be involved in proteolysis. Predicted to localize to collagen-containing extracellular matrix. Is expressed in several structures, including digestive system; eye; gonad; heart; and immune system. Orthologous to human ADAMTS8 (ADAM metallopeptidase with thrombospondin type 1 motif 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adamts8a Human Ortholog
No data available
Associated With adamts8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR010294 ADAMTS/ADAMTS-like, Spacer 1
Domain IPR041645 ADAMTS, cysteine-rich domain 2
Domain IPR045371 ADAMTS/ADAMTS-like, cysteine-rich domain 3
Family IPR013273 ADAMTS/ADAMTS-like
Family IPR013277 Peptidase M12B, ADAM-TS8
Family IPR050439 ADAMTS and ADAMTS-like
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length ADAMTS/ADAMTS-like ADAMTS/ADAMTS-like, cysteine-rich domain 3 ADAMTS/ADAMTS-like, Spacer 1 ADAMTS and ADAMTS-like ADAMTS, cysteine-rich domain 2 Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Peptidase M12B, ADAM-TS8 Peptidase M12B, propeptide Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:A0A8M9QEM5 940
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA adamts8a-201 (1) Ensembl 2,653 nt
mRNA adamts8a-202 (1) Ensembl 1,371 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations