Gene
dapk1
- ID
- ZDB-GENE-060526-177
- Name
- death-associated protein kinase 1
- Symbol
- dapk1 Nomenclature History
- Previous Names
-
- si:ch211-66i11.1
- wu:fj09c03
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in apoptotic process; protein phosphorylation; and signal transduction. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human DAPK1 (death associated protein kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhou et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000488 | Death domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR020676 | Death-associated protein kinase 1, catalytic domain |
| Domain | IPR020859 | Roc domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Death-associated protein kinase 1, catalytic domain | Death domain | Death-like domain superfamily | P-loop containing nucleoside triphosphate hydrolase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Roc domain | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A5WVL9
|
1439 |
Interactions and Pathways
No data available
Plasmids
No data available