Gene
prdm8b
- ID
- ZDB-GENE-060526-174
- Name
- PR domain containing 8b
- Symbol
- prdm8b Nomenclature History
- Previous Names
-
- si:ch211-57h10.4
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity and nucleic acid binding activity. Predicted to be involved in oligodendrocyte development. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 10. Is expressed in adaxial cell and nervous system. Orthologous to human PRDM8 (PR/SET domain 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| progressive myoclonus epilepsy 10 | Alliance | ?Epilepsy, progressive myoclonic, 10 | 616640 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001214 | SET domain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Domain | IPR044402 | PRDM8-like, PR/SET domain |
| Family | IPR052296 | Transcriptional Repressor and Histone Methyltransferase |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Length | PRDM8-like, PR/SET domain | SET domain | SET domain superfamily | Transcriptional Repressor and Histone Methyltransferase | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A2BG51
|
570 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prdm8b-201
(1)
|
Ensembl | 2,502 nt |
Interactions and Pathways
No data available
Plasmids
No data available