Gene

def6c

ID

ZDB-GENE-060503-87

Name

DEF6 guanine nucleotide exchange factor c

Symbol

def6c Nomenclature History

Previous Names

si:dkeyp-15g12.1 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to localize to cytoplasm and nucleus.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Xu et al., 2014

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With def6c Human Ortholog

No data available

Associated With def6c Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001849	Pleckstrin homology domain
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR011993	PH-like domain superfamily

Domain Details Per Protein

Protein	Length	EF-hand domain pair	PH-like domain superfamily	Pleckstrin homology domain
UniProtKB:A0A8M3B1R8 InterPro	552
UniProtKB:A0A8N7UVA8 InterPro	620

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	def6c-201 (1) Ensembl	Ensembl		1,777 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations