Gene

anln2

ID
ZDB-GENE-060503-826
Name
anillin, actin binding protein 2
Symbol
anln2 Nomenclature History
Previous Names
  • si:dkey-238c7.5
  • si:dkey-30c15.10 (1)
  • si:dkey-30c15.9
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have GTP-Rho binding activity. Predicted to be involved in actomyosin contractile ring assembly; protein localization to mitotic actomyosin contractile ring; and septin ring organization. Predicted to localize to actomyosin contractile ring. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Orthologous to human ANLN (anillin actin binding protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With anln2 Human Ortholog
No data available
Associated With anln2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR012966 Anillin homology domain
Domain IPR037840 Anillin, PH domain
Family IPR051364 Cytokinesis and Rho signaling-related protein
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Anillin homology domain Anillin, PH domain Cytokinesis and Rho signaling-related protein PH-like domain superfamily Pleckstrin homology domain
UniProtKB:A0A0A0MPH2
UniProtKB:Q1LX31
UniProtKB:A0A8M9PVN7 941
UniProtKB:A0A8M9PQM5 921
UniProtKB:A0A8M9PFP1 938
UniProtKB:A0A8M9Q6T3 940
UniProtKB:A0A8M9Q2N4 923
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:dkey-30c15.10-201 (1) Ensembl 4,175 nt
mRNA si:dkey-30c15.10-202 (1) Ensembl 6,376 nt
mRNA si:dkey-30c15.10-203 (1) Ensembl 6,457 nt
mRNA si:dkey-30c15.10-204 (1) Ensembl 6,403 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations