Gene
coq8b
- ID
- ZDB-GENE-060503-803
- Name
- coenzyme Q8B
- Symbol
- coq8b Nomenclature History
- Previous Names
-
- adck4 (1)
- si:dkey-114g7.2
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have kinase activity. Involved in glomerular basement membrane development and glomerular visceral epithelial cell development. Predicted to localize to extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 9. Orthologous to human COQ8B (coenzyme Q8B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Burkhalter et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ashraf et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nephrotic syndrome type 9 | Alliance | Nephrotic syndrome, type 9 | 615573 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ABC1 atypical kinase-like domain | ADCK3-like domain | Atypical kinase ADCK | Protein kinase-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A3QJU3
|
624 | ||||
|
UniProtKB:A0A8M9NYH4
|
624 | ||||
|
UniProtKB:A0A8M9PIF5
|
656 |
Interactions and Pathways
No data available
Plasmids
No data available