Gene

edn2

ID

ZDB-GENE-060503-774

Name

endothelin 2

Symbol

edn2 Nomenclature History

Previous Names

si:ch211-202b2.2

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to be involved in regulation of vasoconstriction and vasoconstriction. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human EDN2 (endothelin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Goldman et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With edn2 Human Ortholog

No data available

Associated With edn2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019764	Endothelin-like toxin, conserved site
Domain	IPR001928	Endothelin-like toxin
Family	IPR020475	Endothelin

Domain Details Per Protein

Protein	Length	Endothelin	Endothelin-like toxin	Endothelin-like toxin, conserved site
UniProtKB:Q1MT02 InterPro	164

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	edn2-201 (1) Ensembl	Ensembl		1,775 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations