Gene
scn1ba
- ID
- ZDB-GENE-060503-604
- Name
- sodium channel, voltage-gated, type I, beta a
- Symbol
- scn1ba Nomenclature History
- Previous Names
-
- scn1b
- si:ch211-265p12.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Contributes to voltage-gated sodium channel activity. Involved in sodium ion transport. Predicted to localize to voltage-gated sodium channel complex. Human ortholog(s) of this gene implicated in Brugada syndrome 5; early infantile epileptic encephalopathy 52; familial atrial fibrillation; and generalized epilepsy with febrile seizures plus 1. Is expressed in gill; heart; liver; musculature system; and nervous system. Orthologous to human SCN1B (sodium voltage-gated channel beta subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Brugada syndrome 5 | Alliance | Brugada syndrome 5 | 612838 |
Brugada syndrome 5 | Alliance | Cardiac conduction defect, nonspecific | 612838 |
developmental and epileptic encephalopathy 52 | Alliance | Developmental and epileptic encephalopathy 52 | 617350 |
familial atrial fibrillation | Alliance | Atrial fibrillation, familial, 13 | 615377 |
generalized epilepsy with febrile seizures plus 1 | Alliance | Generalized epilepsy with febrile seizures plus, type 1 | 604233 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Sodium channel subunit beta-1/beta-3 |
---|---|---|---|---|---|---|
UniProtKB:Q06W32
|
221 | |||||
UniProtKB:A0A8M2B4J3
|
173 | |||||
UniProtKB:Q06W35
|
209 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
scn1ba-201
(1)
|
Havana | 1414 nt | |
mRNA |
scn1ba-202
(1)
|
Havana | 1446 nt | |
mRNA |
scn1ba-203
(1)
|
Havana | 1051 nt | |
mRNA |
scn1ba-205
(1)
|
Ensembl | 321 nt | |
ncRNA |
scn1ba-003
(1)
|
Havana | 598 nt |
Interactions and Pathways
No data available
Plasmids
No data available