Gene
gabbr1b
- ID
- ZDB-GENE-060503-5
- Name
- gamma-aminobutyric acid (GABA) B receptor, 1b
- Symbol
- gabbr1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled GABA receptor activity. Involved in behavioral response to nicotine. Predicted to localize to G protein-coupled receptor heterodimeric complex. Is expressed in central nervous system; eye; female organism; and male organism. Orthologous to human GABBR1 (gamma-aminobutyric acid type B receptor subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Neurodevelopmental disorder with language delay and variable cognitive abnormalities | 620502 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000436 | Sushi/SCR/CCP domain |
Domain | IPR001828 | Receptor, ligand binding region |
Domain | IPR017978 | GPCR family 3, C-terminal |
Family | IPR002455 | GPCR family 3, GABA-B receptor |
Family | IPR002456 | GPCR family 3, gamma-aminobutyric acid receptor, type B1 |
Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
Homologous_superfamily | IPR035976 | Sushi/SCR/CCP superfamily |
Domain Details Per Protein
Protein | Length | GPCR family 3, C-terminal | GPCR family 3, GABA-B receptor | GPCR family 3, gamma-aminobutyric acid receptor, type B1 | Periplasmic binding protein-like I | Receptor, ligand binding region | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:F1QAJ3
|
993 | |||||||
UniProtKB:A0A8M2BHH0
|
994 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
gabbr1b-201
(1)
|
Ensembl | 3446 nt | |
mRNA |
gabbr1b-202
(1)
|
Havana | 3766 nt |
Interactions and Pathways
No data available
Plasmids
No data available