Gene
ago3b
- ID
- ZDB-GENE-060503-452
- Name
- argonaute RISC catalytic component 3b
- Symbol
- ago3b Nomenclature History
- Previous Names
-
- Ago3b (1)
- eif2c3
- eif2c3b
- sb:eu332
- si:dkey-3n22.3
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have endoribonuclease activity, cleaving miRNA-paired mRNA. Predicted to be involved in mRNA catabolic process and miRNA mediated inhibition of translation. Predicted to localize to P-body and RISC complex. Is expressed in several structures, including eye; fin; integument; pleuroperitoneal region; and somite. Orthologous to human AGO3 (argonaute RISC catalytic component 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu332 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003100 | PAZ domain |
Domain | IPR003165 | Piwi domain |
Domain | IPR014811 | Argonaute, linker 1 domain |
Domain | IPR032472 | Argonaute linker 2 domain |
Domain | IPR032473 | Protein argonaute, Mid domain |
Domain | IPR032474 | Protein argonaute, N-terminal |
Domain | IPR045246 | Argonaute-like, PIWI domain |
Family | IPR028603 | Protein argonaute-3 |
Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
Homologous_superfamily | IPR036085 | PAZ domain superfamily |
Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
Domain Details Per Protein
Protein | Length | Argonaute-like, PIWI domain | Argonaute, linker 1 domain | Argonaute linker 2 domain | PAZ domain | PAZ domain superfamily | Piwi domain | Protein argonaute-3 | Protein argonaute, Mid domain | Protein argonaute, N-terminal | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A3KPK0
|
860 | |||||||||||
UniProtKB:A0A8M3AVD2
|
476 | |||||||||||
UniProtKB:K4IKE9
|
867 |
Interactions and Pathways
No data available
Plasmids
No data available