Gene

tinagl1

ID

ZDB-GENE-060503-240

Name

tubulointerstitial nephritis antigen-like 1

Symbol

tinagl1 Nomenclature History

Previous Names

LCN7 (1)
lipocalin-7 (1)
si:dkey-158b13.1

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to enable cysteine-type peptidase activity and peptidase inhibitor activity. Acts upstream of or within embryonic viscerocranium morphogenesis and sprouting angiogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space and lysosome. Orthologous to several human genes including TINAGL1 (tubulointerstitial nephritis antigen like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tinagl1 Human Ortholog

No data available

Associated With tinagl1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR025660	Cysteine peptidase, histidine active site
Active_site	IPR025661	Cysteine peptidase, asparagine active site
Domain	IPR000668	Peptidase C1A, papain C-terminal
Domain	IPR001212	Somatomedin B domain
Domain	IPR008037	Pacifastin domain
Family	IPR013128	Peptidase C1A
Homologous_superfamily	IPR036201	Pacifastin domain superfamily
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily