Gene

ptprua

ID

ZDB-GENE-060503-232

Name

protein tyrosine phosphatase receptor type Ua

Symbol

ptprua Nomenclature History

Previous Names

si:ch211-82g18.1
si:dkey-153p21.2

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to localize to integral component of membrane. Orthologous to human PTPRU (protein tyrosine phosphatase receptor type U).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from van Eekelen et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptprua Human Ortholog

No data available

Associated With ptprua Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR000998	MAM domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR003961	Fibronectin type III
Family	IPR051622	Receptor-type Tyrosine-protein Phosphatases
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	Concanavalin A-like lectin/glucanase domain superfamily	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin domain subtype	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	MAM domain	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Receptor-type Tyrosine-protein Phosphatases	Tyrosine-specific protein phosphatase, PTPase domain	Tyrosine-specific protein phosphatases domain
UniProtKB:A0A2R8QCZ8 InterPro	1478
UniProtKB:A0A8M3AVF9 InterPro	1451
UniProtKB:A0A0R4IMC4 InterPro	1472
UniProtKB:A0A8M3B3F6 InterPro	1475
UniProtKB:F1Q6E0 InterPro	1454
UniProtKB:A0A2R8QPI2 InterPro	1460

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptprua-201 (1) Ensembl	Ensembl	5,837 nt	Select Tool
mRNA	ptprua-202 (1) Ensembl	Ensembl	761 nt	Select Tool
mRNA	ptprua-203 (1) Ensembl	Ensembl	8,305 nt	Select Tool ZFIN BLAST
mRNA	ptprua-204 (1) Ensembl	Ensembl	8,323 nt	Select Tool ZFIN BLAST
mRNA	ptprua-205 (1) Ensembl	Ensembl	8,269 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations