Gene

slc24a1

ID

ZDB-GENE-060503-191

Name

solute carrier family 24 member 1

Symbol

slc24a1 Nomenclature History

Previous Names

si:ch211-117i10.3

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have calcium channel activity and calcium, potassium:sodium antiporter activity. Predicted to be involved in calcium ion transmembrane transport; cellular calcium ion homeostasis; and regulation of synaptic plasticity. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1D. Orthologous to human SLC24A1 (solute carrier family 24 member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Clifford et al., 2022

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc24a1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
congenital stationary night blindness 1D	Alliance	Night blindness, congenital stationary (complete), 1D, autosomal recessive	613830

Associated With slc24a1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004837	Sodium/calcium exchanger membrane region
Family	IPR004481	Sodium/potassium/calcium exchanger
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR044880	NCX, central ion-binding domain superfamily

Domain Details Per Protein

Protein	Length	Armadillo-type fold	NCX, central ion-binding domain superfamily	Sodium/calcium exchanger membrane region	Sodium/potassium/calcium exchanger
UniProtKB:A0A8M9Q2S5 InterPro	724
UniProtKB:A0A2R8RLA2 InterPro	696
UniProtKB:A0A8M3B2X1 InterPro	696
UniProtKB:A0A8M3AJK7 InterPro	741
UniProtKB:A0A8M9P1C0 InterPro	741
UniProtKB:F1R8N3 InterPro	724

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	slc24a1-201 (1) Ensembl	Ensembl	2,325 nt	Select Tool ZFIN BLAST
mRNA	slc24a1-202 (1) Ensembl	Ensembl	3,753 nt	Select Tool
mRNA	slc24a1-203 (1) Ensembl	Ensembl	2,241 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations