Gene
pold1
- ID
- ZDB-GENE-060429-1
- Name
- polymerase (DNA directed), delta 1, catalytic subunit
- Symbol
- pold1 Nomenclature History
- Previous Names
-
- fla
- flat head
- im:7139126
- zgc:152688
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable 3'-5'-exodeoxyribonuclease activity and DNA-directed DNA polymerase activity. Acts upstream of or within DNA replication. Predicted to be located in nucleus. Predicted to be part of delta DNA polymerase complex. Is expressed in several structures, including brain; immature eye; neural crest; proliferative region; and retina. Orthologous to human POLD1 (DNA polymerase delta 1, catalytic subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139126 (7 images)
- IMAGE:7160082 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017964 | DNA-directed DNA polymerase, family B, conserved site |
| Domain | IPR006133 | DNA-directed DNA polymerase, family B, exonuclease domain |
| Domain | IPR006134 | DNA-directed DNA polymerase, family B, multifunctional domain |
| Domain | IPR025687 | C4-type zinc-finger of DNA polymerase delta |
| Family | IPR006172 | DNA-directed DNA polymerase, family B |
| Family | IPR050240 | DNA polymerase type-B |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR023211 | DNA polymerase, palm domain superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
| Homologous_superfamily | IPR042087 | DNA polymerase family B, thumb domain |
| Homologous_superfamily | IPR043502 | DNA/RNA polymerase superfamily |
Domain Details Per Protein
| Protein | Length | C4-type zinc-finger of DNA polymerase delta | DNA-directed DNA polymerase, family B | DNA-directed DNA polymerase, family B, conserved site | DNA-directed DNA polymerase, family B, exonuclease domain | DNA-directed DNA polymerase, family B, multifunctional domain | DNA polymerase family B, thumb domain | DNA polymerase, palm domain superfamily | DNA polymerase type-B | DNA/RNA polymerase superfamily | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q2KNE0
|
1105 |
Interactions and Pathways
No data available
Plasmids
No data available