Gene
samd11
- ID
- ZDB-GENE-060428-2
- Name
- sterile alpha motif domain containing 11
- Symbol
- samd11 Nomenclature History
- Previous Names
-
- samd11l (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and metal ion binding activity. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Orthologous to human SAMD11 (sterile alpha motif domain containing 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la028509Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la028510Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa13428 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa43976 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 4 of 4
Show
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000770 | SAND domain |
| Domain | IPR001660 | Sterile alpha motif domain |
| Family | IPR050548 | Polycomb group and chromatin remodeling factors |
| Homologous_superfamily | IPR010919 | SAND-like domain superfamily |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
1 - 5 of 5
Domain Details Per Protein
| Protein | Length | Polycomb group and chromatin remodeling factors | SAND domain | SAND-like domain superfamily | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PWY4
|
600 | |||||
|
UniProtKB:A0A8M9PWU9
|
614 | |||||
|
UniProtKB:A0A8M3AMZ4
|
858 | |||||
|
UniProtKB:A0A8M9PL54
|
715 | |||||
|
UniProtKB:A0A8M9Q7Z7
|
584 |
1 - 5 of 6 Show all
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
samd11-202
(1)
|
Ensembl | 1,054 nt | ||
| mRNA |
samd11-201
(1)
|
Ensembl | 848 nt | ||
| mRNA |
samd11-203
(1)
|
Ensembl | 4,308 nt | ||
| mRNA |
samd11-204
(1)
|
Ensembl | 2,130 nt |
1 - 4 of 4
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-24D19 | ||
| Contained in | BAC | DKEY-98J1 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_009296907 (1) | 4784 nt | ||
| Genomic | GenBank:AL845437 (1) | 239084 nt | ||
| Polypeptide | UniProtKB:E7F6B2 (1) | 874 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Crespo, B., Lan-Chow-Wing, O., Rocha, A., Zanuy, S., Gómez, A. (2013) foxl2 and foxl3 are two ancient paralogs that remain fully functional in teleosts. General and comparative endocrinology. 194:81-93
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
- Inoue, T., Terada, K., Furukawa, A., Koike, C., Tamaki, Y., Araie, M., and Furukawa, T. (2006) Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells. BMC Developmental Biology. 6:15
1 - 5 of 5
Show