Gene
cubn
- ID
- ZDB-GENE-060228-6
- Name
- cubilin (intrinsic factor-cobalamin receptor)
- Symbol
- cubn Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Is expressed in pronephric duct; pronephric tubule; proximal convoluted tubule; and proximal straight tubule. Orthologous to human CUBN (cubilin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Park et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
megaloblastic anemia | Alliance | Imerslund-Grasbeck syndrome 1 | 261100 |
[Proteinuria, chronic benign] | 618884 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR013032 | EGF-like, conserved site |
Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
Domain | IPR000742 | EGF-like domain |
Domain | IPR000859 | CUB domain |
Domain | IPR001881 | EGF-like calcium-binding domain |
Domain | IPR024731 | EGF domain |
Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
Family | IPR050841 | Developmental metalloproteases and endocytic receptors |
Homologous_superfamily | IPR035914 | Spermadhesin, CUB domain superfamily |
PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
Protein | Length | CUB domain | Developmental metalloproteases and endocytic receptors | EGF domain | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like, conserved site | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | NOTCH1 EGF-like calcium-binding domain | Spermadhesin, CUB domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9PME6
|
3626 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available