Gene

ccn5

ID

ZDB-GENE-060223-1

Name

cellular communication network factor 5

Symbol

ccn5 Nomenclature History

Previous Names

ccn5
wisp2
zWISP2-c23 (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have heparin binding activity and integrin binding activity. Predicted to be involved in cell adhesion; negative regulation of cell death; and signal transduction. Predicted to localize to extracellular matrix. Is expressed in pharyngeal arch. Orthologous to human CCN5 (cellular communication network factor 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Fernando et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ccn5 Human Ortholog

No data available

Associated With ccn5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000867	Insulin-like growth factor-binding protein, IGFBP
Domain	IPR001007	VWFC domain
Domain	IPR006207	Cystine knot, C-terminal
Domain	IPR006208	Glycoprotein hormone subunit beta
Domain	IPR043973	CCN, TSP1 domain
Family	IPR050941	Cellular Communication Network Factor
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat

Domain Details Per Protein

Protein	Length	CCN, TSP1 domain	Cellular Communication Network Factor	Cystine knot, C-terminal	Glycoprotein hormone subunit beta	Growth factor receptor cysteine-rich domain superfamily	Insulin-like growth factor-binding protein, IGFBP	Thrombospondin type-1 (TSP1) repeat	Thrombospondin type-1 (TSP1) repeat superfamily	VWFC domain
UniProtKB:D0E2V9 InterPro	344

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ccn5-201 (1) Ensembl	Ensembl	1,406 nt	Select Tool ZFIN BLAST
mRNA	wisp2-202 (1) Ensembl	Ensembl	428 nt	Select Tool
mRNA	wisp2-203 (1) Ensembl	Ensembl	508 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations