Gene
grm2b
- ID
- ZDB-GENE-060201-5
- Name
- glutamate receptor, metabotropic 2b
- Symbol
- grm2b Nomenclature History
- Previous Names
-
- grm2
- gb:kf234084
- mglur2b (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have group II metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to localize to integral component of plasma membrane. Is expressed in brain. Orthologous to human GRM2 (glutamate metabotropic receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Haug et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017979 | GPCR, family 3, conserved site |
| Domain | IPR001828 | Receptor, ligand binding region |
| Domain | IPR011500 | GPCR, family 3, nine cysteines domain |
| Domain | IPR017978 | GPCR family 3, C-terminal |
| Family | IPR000162 | GPCR, family 3, metabotropic glutamate receptor |
| Family | IPR000337 | GPCR, family 3 |
| Family | IPR001458 | GPCR, family 3, metabotropic glutamate receptor 2 |
| Family | IPR050726 | Metabotropic Glutamate Receptor |
| Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
| Homologous_superfamily | IPR038550 | GPCR, family 3, nine cysteines domain superfamily |
Domain Details Per Protein
| Protein | Length | GPCR, family 3 | GPCR, family 3, conserved site | GPCR family 3, C-terminal | GPCR, family 3, metabotropic glutamate receptor | GPCR, family 3, metabotropic glutamate receptor 2 | GPCR, family 3, nine cysteines domain | GPCR, family 3, nine cysteines domain superfamily | Metabotropic Glutamate Receptor | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F7E9
|
874 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance