Gene

crybb2

ID
ZDB-GENE-060130-1
Name
crystallin, beta B2
Symbol
crybb2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in eye and lens. Human ortholog(s) of this gene implicated in cataract and cataract 3 multiple types. Orthologous to human CRYBB2 (crystallin beta B2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa34464Allele with one point mutationUnknownSplice SiteENU
sa34465Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With crybb2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cataract 3 multiple types Alliance Cataract 3, multiple types 601547
1 - 1 of 1
Associated With crybb2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001064 Beta/gamma crystallin
Family IPR050252 Beta/Gamma-Crystallin
Homologous_superfamily IPR011024 Gamma-crystallin-like
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Domain Details Per Protein
Protein Length Beta/gamma crystallin Beta/Gamma-Crystallin Gamma-crystallin-like
UniProtKB:Q52JI4 208
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 8
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA crybb2-201 (1) Ensembl 942 nt
mRNA crybb2-202 (1) Ensembl 771 nt
ncRNA crybb2-003 (1) Ensembl 795 nt
ncRNA crybb2-004 (1) Ensembl 413 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-260H7ZFIN Curated Data
EncodescDNAMGC:172269ZFIN Curated Data
EncodescDNAMGC:194277ZFIN Curated Data
EncodescDNAMGC:194302ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanCRYBB222
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseCrybb25
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 9 of 9
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