Gene
numbl
- ID
- ZDB-GENE-051113-340
- Name
- NUMB like endocytic adaptor protein
- Symbol
- numbl Nomenclature History
- Previous Names
-
- znumb (1)
- zgc:123031
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have cadherin binding activity. Involved in determination of left/right symmetry; negative regulation of Notch signaling pathway; and primitive erythrocyte differentiation. Localizes to cytoplasm. Is expressed in immature eye; integument; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human NUMBL (NUMB like endocytic adaptor protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Bresciani et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NUMB domain | Numb/numb-like | PH-like domain superfamily | PTB/PI domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A286Y8T8
|
640 | ||||
|
UniProtKB:A0A0R4IDU4
|
618 |
Interactions and Pathways
No data available
Plasmids
No data available