Gene

hapln1b

ID

ZDB-GENE-050920-1

Name

hyaluronan and proteoglycan link protein 1b

Symbol

hapln1b Nomenclature History

Previous Names

hapln1
id:ibd5023
wu:fc07e11

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable hyaluronic acid binding activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in extracellular region. Is expressed in blood island; cardiovascular system; hypochord; and mesoderm. Orthologous to human HAPLN1 (hyaluronan and proteoglycan link protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Gomez et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hapln1b Human Ortholog

No data available

Associated With hapln1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000538	Link domain
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR050691	Hyaluronan-binding Proteoglycan
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	C-type lectin fold	C-type lectin-like/link domain superfamily	Hyaluronan-binding Proteoglycan	Immunoglobulin domain subtype	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin V-set domain	Link domain
UniProtKB:E7FBW8 InterPro	353

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	hapln1b-201 (1) Ensembl	Ensembl	4,825 nt	Select Tool ZFIN BLAST
mRNA	hapln1b-202 (1) Ensembl	Ensembl	214 nt	Select Tool ZFIN BLAST
mRNA	hapln1b-203 (1) Ensembl	Ensembl	5,043 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations