Gene
nde1
- ID
- ZDB-GENE-050913-61
- Name
- nudE neurodevelopment protein 1
- Symbol
- nde1 Nomenclature History
- Previous Names
-
- fb82g01
- im:7141877
- wu:fb82g01
- zgc:114109
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable microtubule binding activity. Acts upstream of or within regulation of cell projection size. Predicted to be located in cytoplasm; microtubule; and spindle. Predicted to be part of kinesin complex. Predicted to be active in centrosome and kinetochore. Human ortholog(s) of this gene implicated in lissencephaly 4. Orthologous to human NDE1 (nudE neurodevelopment protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lissencephaly 4 | Alliance | Lissencephaly 4 (with microcephaly) | 614019 |
| Microhydranencephaly | 605013 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NUDE domain | NUDE family |
|---|---|---|---|
|
UniProtKB:Q4V8W6
|
336 |
Interactions and Pathways
No data available
Plasmids
No data available