Gene
tmem106bb
- ID
- ZDB-GENE-050913-37
- Name
- transmembrane protein 106Bb
- Symbol
- tmem106bb Nomenclature History
- Previous Names
-
- zgc:114147
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to be involved in dendrite morphogenesis and lysosome localization. Predicted to localize to lysosomal membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human TMEM106B (transmembrane protein 106B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypomyelinating leukodystrophy 16 | Alliance | Leukodystrophy, hypomyelinating, 16 | 617964 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Transmembrane protein 106 | Transmembrane protein 106, C-terminal domain | Transmembrane protein 106, N-terminal |
|---|---|---|---|---|
|
UniProtKB:Z4YHQ6
|
267 | |||
|
UniProtKB:Q1LWC2
|
267 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem106bb-201
(1)
|
Ensembl | 1,189 nt |
Interactions and Pathways
No data available
Plasmids
No data available