Gene
dgat2
- ID
- ZDB-GENE-050913-15
- Name
- diacylglycerol O-acyltransferase 2
- Symbol
- dgat2 Nomenclature History
- Previous Names
-
- zgc:113394
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have diacylglycerol O-acyltransferase activity. Involved in lipid homeostasis; regulation of response to endoplasmic reticulum stress; and response to (R)-carnitine. Predicted to localize to endoplasmic reticulum membrane; lipid droplet; and perinuclear endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease. Is expressed in male organism. Orthologous to several human genes including DGAT2 (diacylglycerol O-acyltransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from O'Hare et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007130 | Diacylglycerol acyltransferase |
Domain Details Per Protein
| Protein | Length | Diacylglycerol acyltransferase |
|---|---|---|
|
UniProtKB:Q4V9F0
|
361 |
Interactions and Pathways
No data available
Plasmids
No data available