Gene
ndufa12
- ID
- ZDB-GENE-050828-1
- Name
- NADH:ubiquinone oxidoreductase subunit A12
- Symbol
- ndufa12 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in response to oxidative stress. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 23. Orthologous to human NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nuclear type mitochondrial complex I deficiency 23 | Alliance | Mitochondrial complex I deficiency, nuclear type 23 | 618244 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007763 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 |
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 |
|---|---|---|
|
UniProtKB:Q498W6
|
146 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufa12-201
(1)
|
Ensembl | 494 nt |
Interactions and Pathways
No data available
Plasmids
No data available