Gene
snx10a
- ID
- ZDB-GENE-050809-44
- Name
- sorting nexin 10a
- Symbol
- snx10a Nomenclature History
- Previous Names
-
- im:7153949
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable phosphatidylinositol phosphate binding activity. Involved in Kupffer's vesicle development; cilium assembly; and left/right axis specification. Acts upstream of or within heart looping. Predicted to be located in cytoskeleton and endosome membrane. Predicted to be active in endosome. Predicted to colocalize with centrosome. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 8. Orthologous to human SNX10 (sorting nexin 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7153949 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive osteopetrosis 8 | Alliance | Osteopetrosis, autosomal recessive 8 | 615085 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Phox homology | PX domain superfamily | Sorting nexin-10/11 |
|---|---|---|---|---|
|
UniProtKB:A0A8M9P1S3
|
229 | |||
|
UniProtKB:F1Q506
|
229 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
snx10a-201
(1)
|
Ensembl | 1,609 nt | ||
| mRNA |
snx10a-202
(1)
|
Ensembl | 1,567 nt | ||
| mRNA |
snx10a-203
(1)
|
Ensembl | 1,880 nt | ||
| mRNA |
snx10a-204
(1)
|
Ensembl | 1,741 nt |
Interactions and Pathways
No data available
Plasmids
No data available