Gene
pygo2
- ID
- ZDB-GENE-050809-108
- Name
- pygopus homolog 2 (Drosophila)
- Symbol
- pygo2 Nomenclature History
- Previous Names
-
- fc56f02
- wu:fc46c10
- wu:fc56f02
- wu:fi37d10
- wu:fj66f08
- wu:fy30b05
- zgc:111854
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Acts upstream of or within embryonic viscerocranium morphogenesis and regulation of canonical Wnt signaling pathway involved in heart development. Orthologous to human PYGO2 (pygopus family PHD finger 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Shull et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Family | IPR052475 | Wnt Signal Transduction Protein |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | Wnt Signal Transduction Protein | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q1L8T6
|
571 | ||||||
|
UniProtKB:A0A8M2B671
|
556 |
Interactions and Pathways
No data available
Plasmids
No data available