Gene
hamp
- ID
- ZDB-GENE-050726-1
- Name
- hepcidin antimicrobial peptide
- Symbol
- hamp Nomenclature History
- Previous Names
-
- hamp1
- hamp2
- hep (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Exhibits lipopolysaccharide binding activity; lipoteichoic acid binding activity; and peptidoglycan binding activity. Involved in cellular response to progesterone stimulus; defense response to bacterium; and iron ion homeostasis. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in anemia; hemochromatosis; hemochromatosis type 2B; and hepatocellular carcinoma. Is expressed in blood plasma; gut; intestine; and liver. Orthologous to human HAMP (hepcidin antimicrobial peptide).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 34 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Jiang et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hemochromatosis type 2B | Alliance | Hemochromatosis, type 2B | 613313 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR010500 | Hepcidin |
Domain Details Per Protein
| Protein | Length | Hepcidin |
|---|---|---|
|
UniProtKB:A0A8M1P6E9
|
90 | |
|
UniProtKB:Q7T273
|
91 | |
|
UniProtKB:P61516
|
91 |
Interactions and Pathways
No data available
Plasmids
No data available