Gene

dpysl5b

ID

ZDB-GENE-050720-4

Name

dihydropyrimidinase like 5b

Symbol

dpysl5b Nomenclature History

Previous Names

CRMP-5b (1)
si:ch211-152c2.6

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Predicted to be involved in axon guidance. Predicted to localize to cytosol. Is expressed in central nervous system and trigeminal ganglion. Orthologous to human DPYSL5 (dihydropyrimidinase like 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dpysl5b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Ritscher-Schinzel syndrome 4	619435

Associated With dpysl5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006680	Amidohydrolase-related
Family	IPR011778	Hydantoinase/dihydropyrimidinase
Family	IPR050378	Metallo-dependent Hydrolases Superfamily
Homologous_superfamily	IPR011059	Metal-dependent hydrolase, composite domain superfamily
Homologous_superfamily	IPR032466	Metal-dependent hydrolase