Gene
spty2d1
- ID
- ZDB-GENE-050522-212
- Name
- SPT2 chromatin protein domain containing 1
- Symbol
- spty2d1 Nomenclature History
- Previous Names
-
- wu:fb01d08
- zgc:111826
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity; RNA polymerase I core binding activity; and histone binding activity. Predicted to be involved in nucleosome assembly; regulation of DNA-templated transcription; and transcription by RNA polymerase I. Predicted to be located in nucleus. Predicted to be active in nucleolus. Is expressed in axial mesoderm; hatching gland; notochord; polster; and telencephalon. Orthologous to human SPTY2D1 (SPT2 chromatin protein domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:111826 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR013256 | Chromatin SPT2 |
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Domain Details Per Protein
| Protein | Length | Chromatin SPT2 |
|---|---|---|
|
UniProtKB:A0A8M6YWI0
|
629 | |
|
UniProtKB:Q6DGN6
|
629 | |
|
UniProtKB:F1R3H5
|
632 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spty2d1-201
(1)
|
Ensembl | 6,717 nt | ||
| mRNA |
spty2d1-202
(1)
|
Ensembl | 2,876 nt | ||
| mRNA |
spty2d1-203
(1)
|
Ensembl | 760 nt | ||
| ncRNA |
spty2d1-003
(1)
|
Ensembl | 866 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-286F11 | ZFIN Curated Data | |
| Contained in | BAC | DKEYP-19E1 | ZFIN Curated Data | |
| Encodes | EST | fb01d08 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:111826 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001159971 (1) | 2609 nt | ||
| Genomic | GenBank:BX005383 (1) | 142728 nt | ||
| Polypeptide | UniProtKB:F1R3H5 (1) | 632 aa |
- Raman, R., Fallatah, W., Al Qaryoute, A., Dhinoja, S., Jagadeeswaran, P. (2021) Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target. Scientific Reports. 11:15238
- Fongang, B., Kudlicki, A. (2016) Comparison between Timelines of Transcriptional Regulation in Mammals, Birds, and Teleost Fish Somitogenesis. PLoS One. 11:e0155802
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Krens, S.F., Corredor-Adamez, M., He, S., Snaar-Jagalska, B.E., and Spaink, H.P. (2008) ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis. BMC Genomics. 9:196
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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