Gene
abca3b
- ID
- ZDB-GENE-050517-2
- Name
- ATP-binding cassette, sub-family A (ABC1), member 3b
- Symbol
- abca3b Nomenclature History
- Previous Names
-
- abca3
- si:ch211-155i15.6
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to localize to intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Is expressed in swim bladder. Orthologous to human ABCA3 (ATP binding cassette subfamily A member 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
pulmonary alveolar proteinosis | Alliance | Surfactant metabolism dysfunction, pulmonary, 3 | 610921 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR017871 | ABC transporter-like, conserved site |
Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
Domain | IPR003593 | AAA+ ATPase domain |
Domain | IPR013525 | ABC-2 type transporter, transmembrane domain |
Family | IPR026082 | ABC transporter A |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
Protein | Length | AAA+ ATPase domain | ABC-2 type transporter, transmembrane domain | ABC transporter A | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9Q293
|
1703 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
abca3b-201
(1)
|
Ensembl | 5112 nt | |
mRNA |
abca3b-202
(1)
|
Havana | 4994 nt | |
mRNA |
abca3b-203
(1)
|
Ensembl | 5265 nt |
Interactions and Pathways
No data available
Plasmids
No data available