Gene
ccnd2b
- ID
- ZDB-GENE-050420-354
- Name
- cyclin D2, b
- Symbol
- ccnd2b Nomenclature History
- Previous Names
-
- si:ch211-240j22.2
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to contribute to protein kinase activity. Predicted to be involved in mitotic cell cycle phase transition; positive regulation of G1/S transition of mitotic cell cycle; and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to localize to cyclin-dependent protein kinase holoenzyme complex; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; invasive lobular carcinoma; prostate cancer; and transitional cell carcinoma. Orthologous to human CCND2 (cyclin D2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Grainger et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 | 615938 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cyclin | Cyclin, C-terminal domain | Cyclin-like domain | Cyclin-like superfamily | Cyclin, N-terminal | Cyclins, cyclin-box |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q1L8M6
|
295 | ||||||
|
UniProtKB:A0A8M2BBN7
|
330 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccnd2b-201
(1)
|
Ensembl | 2,538 nt |
Interactions and Pathways
No data available
Plasmids
No data available